Penedo is a municipality in the state of Alagoas in Brazil. The population is 63,846 (2020 est.) in an area of 689.88 sqkm. Penedo lies 173 km south-west of the state capital of Maceió.
Founded in 1614, Penedo has many important examples of Portuguese and Dutch colonial architectures. The history of Penedo can be found in Francisco Alberto Sales's book Arruando para o Forte. It was reached by sea from the wide estuary of the São Francisco River.
The unclassified extinct Wakoná language was formerly spoken in Penedo. Loukotka (1968) reported that the remaining ethnic descendants who speak only Portuguese could be found in the city of Porto Real do Colégio.
