Map - Coquimbo Region (Región de Coquimbo)

The Coquimbo Region (Región de Coquimbo, ) is one of Chile's 16 regions (first order administrative divisions). It is bordered by Atacama to the north, Valparaíso to the south, Argentina to the east, and the Pacific Ocean to the west. It is approximately 400 km north of the national capital, Santiago.

The capital and largest city is La Serena. Other important cities include the seaport Coquimbo and the agricultural centre Ovalle.

The Coquimbo Region forms the narrowest part, or 'waist' of Chile, and is hence one of the country's more mountainous regions, as the Andes range runs closer to the sea than elsewhere. The region has notable marine species as well as taxa that are associated with the mountainous regions. With respect to marine organisms, the upwelling areas encourage bioproductivity off of this Pacific Coast area of Chile.

In the southern mountainous areas of the Coquimbo Region, the rare and endangered Chilean Wine Palm is found, whose habitat is threatened by human population growth in the region and associated deforestation for residential expansion and agriculture.

The Elqui Valley is home to a number of astronomical observatories, owing to the region's clear skies. It is also home to a 640-meter-long dam, the Puclaro, which confines the Elqui River and produces a reservoir containing 4,630,000 m³ of water for agricultural irrigation.